Antimicrobial Agents Production by Marine Streptomyces exfoliatus Coculture with Staphylococcus aureus

Authors

  • Hani Moubasher Department of Botany and Microbiology, Faculty of Science, Cairo University, Giza 12613, Egypt.
  • Mohamed Ez El Din Department of Botany and Microbiology, Faculty of Science, Cairo University, Giza 12613, Egypt.
  • Lamiaa Salah Pilot Plant Unit in Applied Research Department in Vacsera, 51-22311, Egypt.
  • Manar Mohamed Barakat Department of Botany and Microbiology, Faculty of Science, Cairo University, Giza 12613, Egypt.

Keywords:

Marine, Staphylococcus, Coculture, Secondary metabolites, Streptomyces exfoliatus

Abstract

In this study, marine Streptomyces exfoliatus was isolated from the Red Sea, Egypt, and was identified using 16s rRNA. S. exfoliatus was fermented on different media under different carbon source concentrations, pH, temperatures, distilled H2O, and sea H2O, under shaking and static conditions. The active material was isolated by chloroform and ethyl acetate extractions then separated by column chromatography and purified by preparative TLC and identified by GC-MS. Methicillin-resistant Staphylococcus aureus inhibited by ß-caryophyllene.

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Published

2023-03-30

Issue

Vol. 12 No. 01 (2023): JANUARY-MARCH 2023

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.