Subclinical Atherosclerosis in Psoriatic Arthritis Patients and its Correlation with Disease Activity and Severity. A review

Authors

  • Abeer A. Hussein Rheumatology, Rehabilitation and Physical Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt
  • Radwa M. EL khouly Rheumatology, Rehabilitation and Physical Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt
  • Mervat I. Hussein Rheumatology, Rehabilitation and Physical Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt
  • Souzan E. Gado Rheumatology, Rehabilitation and Physical Medicine Department, Faculty of Medicine, Tanta University, Tanta, Egypt

Keywords:

Atherosclerosis, psoriatic arthritis, severity, flow mediated dilatation

Abstract

Background: Psoriatic arthritis (PsA) is a chronic, seronegative spondyloarthritis (SpA) that impacts up to 30% of patients with psoriasis. PsA may impact the spine (axial disease), sacroiliac joints, and peripheral joints (peripheral disease). Atherosclerosis is regarded as a significant cardiovascular risk factor. In PsA patients, the precise mechanism of increased early atherosclerosis remains unclear. Chronic inflammation can exacerbate atherosclerosis by causing endothelial dysfunction, both directly and indirectly. The goal of the trial was to ascertain the correlation between the severity and activity of psoriatic arthritis and subclinical atherosclerosis in patients through the use of flow-mediated dilatation (FMD) and carotid intima media thickness (CIMT).

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Published

2024-06-30

Issue

Vol. 13 No. 02 (2024): APRIL-JUNE 2024

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.