Effect of COVID 19 Infection on ST Elevation Myocardial Infarction (STEMI) Patients Managed by Primary PCI

Abstract

A life-threatening cardiovascular-emergency called ST elevation myocardial infarction (STEMI) necessitates immediate intervention for reperfusion. COVID-19 has a negative effect on STEMI patients. The purpose of this work was to contrast individuals who had STEMI and concomitant COVID-19 infection with patients who had STEMI without COVID-19 infection, and both managed by primary percutaneous coronary intervention(PPCI). Methods: This prospective, cohort work was performed on 50 patients with clinical criteria of patients presented by STEMI within 24 hours of symptoms onset with and without concomitant COVID 19 infections managed by PPCI. Participants were split into two equal groups: group A: participants presented by STEMI and concomitant COVID-19 infection diagnosed by polymerase chain reaction and chest computerized tomography c. group B: patients presented by STEMI without COVID 19 infection. Results: No significant variation was discovered among COVID-19 group and non-COVID-19 group as regard major  adverse cardiovascular events (MACE). It was found from the multivariate logistic regression analysis of data that COVID-19 infection significantly delayed time to reperfusion (door to balloon time) and this was associated with worse prognosis and increased rate of MACE. positive C-reactive protein also was significant from multivariate data analysis and this was associated with poor prognosis of STEMI patients. Conclusions: COVID-19 pandemic had a direct effect on the prognosis of individuals with STEMI due to delay from symptoms onset to first medical contact(FMC) and delay in door-to-balloon time.