Impulse Oscillometry in Assessment of Asthma Control in Egyptian Children

Authors

  • Hala G. Elnady Professor of Child Health, Medical Research and Clinical Studies Institute, National Research Centre, 33 El Buhouth ST., 12622, Dokki, Cairo, Egypt.
  • Shahinaz M. Hussien Professor of Pediatrics, Department of Pediatrics, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
  • Dina A. Salah Researcher of Child Health, Medical Research and Clinical Studies Institute, National Research Centre, 33 El Buhouth ST., 12622, Dokki, Cairo, Egypt.
  • Sameh A. Ahmed Lecturer of Pediatrics, Department of Pediatrics, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
  • Sara F. Sallam Assistant Professor of Child Health, Medical Research and Clinical Studies Institute, National Research Centre, 33 El Buhouth ST., 12622, Dokki, Cairo, Egypt.

Keywords:

Oscillometry, Asthma, discrepancy, symptom perception, Egyptian Children

Abstract

Background: Assessing asthma control and early detection of children at risk is challenging due to discrepancy in symptom perception. Traditional spirometry requires children to perform forced expiratory maneuvers while IOS require minimal cooperation. The aim of this study was to determine sensitivity and specificity of IOS compared to clinical asthma control parameters among asthmatic children. Methods: 80 children were enrolled, Group 1 (patients) according to clinical manifestations in GINA (2019), Group 2 (Control), 40 healthy children with matched age, sex, and socioeconomic standard, subjected to history taking, general and chest examination. Family history of atopy and wheezing followed by SPT, IOS was performed in compliance with the ERS/ATS guidelines by Master Screen IOS system. Results: More than one third of group1 were positive to inhaled allergen.R5, R5-R20, Fres and Ax were significantly higher among asthmatics. Bronchodilator response was significant in both controlled and uncontrolled children. There was a significant
association between asthma control clinically and IOS parameter AX < 7 (kPa/L). Assessing asthma control using IOS parameter AX < 7 kPa/L showed 68.18 % sensitivity and 88.89 % specificity. Conclusions: Impulse Oscillometry is a noninvasive, rapid, validated technique that helps in identification of asthma control among asthmatic children using R5, X5, AX as sensitive and specific indicators.

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Published

2023-05-30

Issue

Vol. 12 No. 02 (2023): APRIL-JUNE 2023

Section

Articles

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Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.