Diabetes and COVID-19: Double Health Effect

Authors

  • Alaa Said Raslan Department of Internal Medicine, Faculty of Medicine, Tanta University, Egypt.
  • Engy A. Ibrahim Department of Internal Medicine, Faculty of Medicine, Tanta University, Egypt.
  • Ibrahim S. Eldin Ibrahim Department of Chest, Faculty of Medicine, Tanta University, Egypt.
  • Mohamed Mokhtar Mabrouk Department of Internal Medicine, Faculty of Medicine, Tanta University, Egypt.

Keywords:

Diabetes Mellitus, COVID-19, inflammatory markers, disease severity

Abstract

Background: Both diabetes mellitus and COVID-19 affect each other. Diabetic individuals have a greater risk for infection with high morbidity and mortality. Diabetes individuals with COVID-19 had worsening inflammatory markers and imagin g than COVID 19 individuals without diabetes. Methods: 60 individuals with COVID-19 infection were hospitalized to Tanta Chest University Hospital for a prospective case-control study based on positive PCR results of COVID-19 and were equally divided into 2 groups: study group: diabetic COVID-19 patients and control group: individuals with only COVID-19. All patients underwent history taking, clinical evaluation,
laboratory investigations, and Radiological investigation. Results: Compared to the control group, the study group had substantially greater levels of RBS, HbA1C, CRP, D-Dimer, serum ferritin, liver enzymes, WBC, LDH, urea, Creatinine, procalcitonin, interleukin 6, the severity of COVID-19, and the need for Tocilizumab. Conclusion: diabetic COVID-19 individuals have greater blood pressure, RBS, HbA1C, CRP, D-dimer, Serum ferritin, liver enzymes, procalcitonin, LDH, urea, Creatinine, and interleukin 6 levels in addition to high risk of extreme COVID-19 course comparison to those who are not diabetic. Therefore, tight control of glucose levels is critical in patients with DM to decrease mortality and morbidity.

Published

2023-04-30