Evaluation the Prognostic Value of Peripheral Blood Counts in Covid-19 Patients

Abstract

Background: The outbreak of novel Coronavirus Disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major pandemic situation and a catastrophe for humans. COVID-19 is a severe infectious disease particularly of the respiratory system characterized by fatal complications. In fact, the current crisis of COVID-19 has become an increasingly serious concern to public health. Since there are no specific drugs and/or vaccines available so far and continues gene mutations. COVID-19 patients showed several abnormal hematological findings. Including lymphopenia, neutrophilia, elevated levels of D-dimer and fibrinogen. COVID-19 remains to be a major challenge task. Objective: Our study was conducted to evaluate the prognostic value of peripheral blood counts in Covid- 19 patients. Patients and methods: Our study was a Prospective cohort study. It was conducted on 100 patients with Covid -19 at and post admission Results: there was positive correlation between NLR and PLR with C- reactive
protein (CRP), LDH, ferritin, Procalcitonin, IL 6 and D-dimer along course of the disease. However, LMR was found to be negatively correlated with them. It was found that if NLR and PLR increased there would be an increase in severity of the disease as long as the risk of ICU admission and intubation. Conclusion: Our study revealed that, NLR and PLR in addition to LMR are good prognostic factors in COVID 19 patients that are cost-effective, readily available, and easy to calculate and can be used instead of other inflammatory markers e.g. (CRP, IL6, D-dimer, ferritin and procalcitonin).